Published work appear on Journal Covers

2016


 Lu Z, Piechowicz and Qiu S. A simplified method for ultra-low density, long-term primary hippocampal neuron culture. Journal of Visualized Experiments, in press.

 Peng Y*, Lu Z*, Li G, Piechowicz M, Anderson M, Uddin Y, Wu J and Qiu S. The autism associated MET receptor tyrosine kinase engages early neuronal growth mechanism and controls glutamatergic circuits development in the forebrain. Molecular Psychiatry. *equal contribution. [Cover article]. 2016 Jan 5. Online.

 Ming G, Liu Q, Qiu S, Yang B, Xia K, Li G, Kerrigan JF and Wu J.  Gap junctions contribute to ictal/interictal genesis in human hypothalamic harmartomas. EBioMedicine, 2016, in press.


 
2015

Wu J, Gao M, Shen JX, Qiu S, Kerrigan JF. Mechanisms of intrinsic epileptogenesis in human gelastic seizures with hypothalamic hamartoma. CNS Neurosci Ther. 2015;21(2):104-11.


2014

 McGee AW,  Li G, Lu Z, Qiu S. Convergent synaptic and circuit substrates underlying autism genetic risks. Frontiers in Biology, 2014;(9)2:137-150. [Cover article]

Céleste-Élise Stephany, Leanne L.H. Chan, Sherveen N. Parivash, Hilary M. Dorton, Mariel Piechowicz, Shenfeng Qiu*, and Aaron W. McGee*. Plasticity of binocularity and visual acuity are differentially limited by nogo receptor.  The Journal of Neuroscience. 2014, 34(35):11631-40. *co-correspondent author.

 Li G, Qiu S. Neurodevelopmental underpinnings of Angelman Syndrome. J Bioanal Biomed. 2014, 6:052-056. Review.

 Qiu S*, Lu Z and Levitt P. MET receptor tyrosine kinase controls dendritic complexity, spine morphogenesis, and glutamatergic synapse maturation in the hippocampus". The Journal of Neuroscience. 2014,34(49):16166-79. *correspondent author.


 
2013

Xi G, Hu P, Qu C, Qiu S, Tong C, Ying QL. Induced neural stem cells generated from rat fibroblasts. Genomics Proteomics Bioinformatics. 2013;11(5):312-9.

Peng Y, Huentelman M, Smith C, Qiu S. MET receptor tyrosine kinase as an autism genetic risk factor. Int Rev Neurobiology. 2013;113:135-65.

 
2012

Qiu S, Luo S, Levitt P, Gary G and Knowles J. Single neuron transcriptome profiling using RNA-seq: technical feasibility and reproducibility. Frontiers in Genetics, 2012;3:124.

Qiu S, Aldinger KA, Levitt P. Modeling of autism genetic variations in mice: focusing on synaptic and microcircuit dysfunctions. Dev Neurosci. 2012;34(2-3):88-100.


 
2011

Aldinger KA, Plummer JT, Qiu S, Levitt P. SnapShot: genetics of autism. Neuron. 2011; 72(2):418-8. E1.

Qiu S*, Anderson C*, Levitt PR and Shepherd GMG. Circuit-specific intracortical hyperconnectivity in mice with deletion of the autism-associated Met receptor tyrosine kinase (*co-first author). The Journal of Neuroscience, 2011, 31(15):5855-64.

 

2010

Qiu S, Champagne DL, Peters M, Weeber EJ, Levitt PR and Pimenta AF. Loss of limbic system-associated membrane protein leads to reduced hippocampal mineralocorticoid receptor expression, impaired synaptic plasticity and spatial memory deficit. Biological Psychiatry, 2010,68(2):197-204. [Cover article].

 Aldinger KA, Qiu S. New mouse genetic model duplicates human 15q11-13 autistic phenotypes, or does it? Dis Model Mech. 2010, 3(1-2):3-4.


 
2009

Qiu S, Jebelli AK, Ashe JH and Curras-Collazo MM. Domoic acid induces a long-lasting enhancement of CA1 field responses and impairs tetanus-induced long-term potentiation in rat hippocampal slices. Toxicological Sciences. 2009,111(1):140-150.

 
2008

Fan D, Qiu S,  Weeber EJ, Linton, MF, Fazio, S. Self-association of human PCSK9 enhances its LDLR-degrading activity. Biochemistry,2008, 47(6):1631-9

Tanner DC, Qiu S, Bolognani F, Partridge LD, Weeber EJ and Perrone-Bizzozero, N. Alterations in mossy fiber physiology and GAP-43 expression and function in transgenic mice overexpressing HuD in adult dentate granule cells. Hippocampus, 18(8):814-23

Levenson J, Qiu S and Weeber EJ. The Role of Reelin in Adult Synaptic Function and the Genetic and Epigenetic Regulation of the Reelin Gene. BBA - Gene Regulatory Mechanisms, 2008, 1779(8):422-31


 
2007

Bolognani  F, Qiu  S, Tanner  DC, Paik  J, Perrone-Bizzozero  N I, Weeber  EJ. Associative and spatial learning and memory deficits in transgenic mice overexpressing the RNA-binding protein HuD. Neurobiol Learn Mem. 2007, 87(4): 635-43.

Qiu S, Zhao LF, Korwek KM and Weeber EJ.  Differential coupling with enhanced NMDA and AMPA receptor activity by reelin signaling in the adult hippocampus. The Journal of Neuroscience, 2006, 26(50): 12943-55.

Qiu S, Li L, Weeber EJ and May JM. Ascorbate transport by primary cultured neurons and its role in neuronal function and protection against excitotoxicity. Journal of Neuroscience Research. 2007, 85(5): 1046-56.

Qiu S and Weeber EJ. Reelin signaling facilitates maturation of CA1 glutamatergic synapse. Journal of Neurophysiology, 2007, 97(3):2312-21. [Cover article].

van Woerden GM, Gustin RM, Qiu S, Hojjati MR, Harris KD, Avila-Freire R, Jiang YH, Elgersma, Y and Weeber EJ. Rescue of neurological deficits in a mouse model for Angelman Syndrome by reduction of CaMKII inhibitory phosphorylation. Nature Neuroscience, 2007, 10(3)280-2.

Fan D, Qiu S, Overton CD, Yancey PG, Swift LL, Jerome WG, Linton MF and Fazio S. Impaired secretion of apolipoprotein E2 from macrophages. Journal of Biological Chemistry, 2007, 282 (18): 13746-53.

 
2006    

Qiu, S. Chong w. Pak and Curras-Collazo, M. C. Sequential involvement of distinct glutamate receptors in domoic acid-induced neurotoxicity in rat mixed cortical cultures: effect of multiple dose/duration paradigms, chronological age, and repeated exposure. Toxicological Sciences. 2006, 89(1):243-256.

Beffert U, Weeber EJ, Durudas A, Qiu S, Masiulis I, Sweatt JD, Li WP, Adelmann G, Frotscher M, Hammer RE, Herz J. Modulation of synaptic plasticity and memory by Reelin involves differential splicing of the lipoprotein receptor Apoer2. Neuron. 2005. 47:567-579.

Qiu S, Korwek KM, Weeber EJ. A fresh look at an ancient receptor family: Emerging roles for low density lipoprotein receptors in synaptic plasticity and memory formation. Neurobiol Learn Mem. 2006, 85(1):16-29.

Qiu, S, Korwek KM, Pratt-Davis A, Peters M, Bergman MY and Weeber EJ. Cognitive disruption and altered hippocampus synaptic function in Reelin haploinsufficient mice. Neurobiol Learning Mem. 2006, 85(3):228-242 [Cover ariticle].

Qiu, S. and Curras-Collazo, M.C. Histopathological and molecular changes produced by hippocampal microinjection of domoic acid. Neurotoxicology and Teratology, 2006, 28(3):354-362.