Brain Mechanisms of Neurodevelopmental Disorders

 Shenfeng Qiu Laboratory

The Qiu laboratory is dedicated to the understanding of the origins of neurodevelopmental and neuropsychiatric disorders, in which there is clear genetic components play an important role in the pathogenesis.  Most efforts focusing on autism spectrum disorders, such as autism and Angelman syndrome. We are also interested in neurocircuit mechanisms and brain maladaptive changes underlying neuropsychiatric conditions, such as schizophrenia and major depression.

Our work leverages the power of genetic mouse models, coupled with basic neurobiology, neuroanatomy, electrophysiology, and behavior to obtain a system-level understanding of disease mechanisms.